Sponsored by Toskani US
Innovative technologies have helped shift aesthetics towards regenerative medicine, and Toskani US® (Fort Lauderdale, Fla.) is making it easy for aesthetic practices to keep up with patient demand. The Company offers a full range of topicals along with their newly acquired Exceed mesotherapy device.
“I have always treated my patients in a very specialized way,” said facial plastic surgeon Luis Assis, MD (Ipatinga, Brazil). Toskani® came with the possibility of creating even more individualized protocols. The Company’s new stars include non-crosslinked hyaluronic acids (HA), biomimetic peptides and sodium deoxyribonucleic acid of salmon milt (DNA-Na). I mainly use Toskani’s whitening complex poli revitalizing (WCPR), a brightening complex which is a super blend of liposomal active ingredients with peptides that deliver ten times more than similar products. It can be used with various technologies such as lasers and microneedling. I drip about 1 mL to 2 mL after the technology and massage for one minute to ensure greater absorption and reservoir of actives.”
Toskani MED® is highly regarded for professional- grade cosmetic products that were created primarily for clinical use. In addition to WCPR, products include nutritive complex poli revitalizing (NCPR), a peptide-based mesotherapy treatment, and eye complex poli revitalizing (ECPR), a peptide-based mesotherapy cocktail for the eyes. Lumicen is Toskani’s highly polymerized DNA-Na to treat wrinkles and dry, dull skin.
“This line of regenerators that act by regulating the senescence phenotype (on fibroblasts, immunological cells and keratinocytes) are absolutely necessary in my daily practice,” Dr. Assis continued. “The DNA sodium salt found in the Lumicen line is derived from salmon gametes and is pure. Using Lumicen as a drug delivery after CO2 laser or any ablative procedure ensures much faster tissue recovery and less downtime for the patient.”
Plastic surgeon Carlos Bautzer, MD incorporates Toskani technologies into his aesthetic practice in São Paulo, Brazil. “I use the products throughout my surgeries and apply them with the Exceed device. During pre-op, I use the A-OX 360 cocktail for enhancing the skin quality. During surgery I use CO2 with Lumicen, and post-surgery I use the Toskani Revitalizing Cocktail, which is especially made for scars and marks on the skin,” he stated. “I also use Exceed to apply hair complex poli revitalizing (HCPR) for effective mesotherapy for the hair.”
Shino Bay Aguilera, DO, a board-certified dermatologist in Fort Lauderdale, Fla., uses NCPR to enhance the effects of biocollagen stimulators. “By supplying the extracellular matrix with optimal amounts of signaling peptides, cofactors, 
vitamins and HA, we support fibroblasts in thriving and performing at their best,” Dr. Aguilera reported. “Our recent publication in the Journal of Drugs in Dermatology, released in September 2023, highlights the success of our synergistic approach. The study, conducted by Elina Theodorakopoulou, MD in Greece, employed a unique poly revitalizing solution not available in the U.S. The findings revealed a remarkable increase in dermal thickness – 45.89% at three weeks and 65.39% at six weeks.1 Excitingly, we are now able to replicate this Bionutriblend technique in the U.S. using NCPR.”
Since the publication, many have adopted and embraced the innovative concept of skin priming for other biocollagen stimulators, such as poly-l-lactic acid (professor Alessio Redaelli in Milan, Italy), achieving comparable results by transforming a depleted and compromised extracellular matrix. “This will not just be a passing trend; it is destined to become the new gold standard,” Dr. Aguilera added. “This progressive approach to critical thinking deepens our understanding of the aging process at a cellular level, unlocking the potential for novel ways to reverse the aging process.”
References:
1. Theodorakopoulou, E., McCarthy, A., Perico, V., & Aguilera, S. B. (2023). Optimizing Skin Regenerative Response to Calcium Hydroxylapatite Microspheres Via Poly-Micronutrient Priming. Journal of Drugs in Dermatology. https://doi.org/ https://jddonline.com/articles/optimizing-skin-regenerativeresponse- to-calcium-hydroxylapatite-microspheres-via-polymicronutrient- priming-S1545961623P0925X
